Diphenhydramine and phenylephrine and Isopto Eserine
Determining the interaction of Diphenhydramine and phenylephrine and Isopto Eserine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:DiphenhydrAMINE may reduce the effects of physostigmine ophthalmic. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor
Professional:MONITOR: Theoretically, anticholinergic agents and other agents with significant anticholinergic activity (e.g., antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide) may antagonize the effects of topically administered cholinergic agents such as acetylcholine, carbachol, demecarium, echothiophate, isoflurophate, physostigmine, and pilocarpine. The proposed mechanism involves opposing pharmacodynamic action on muscarinic receptor sites in ocular tissue. This interaction is sometimes desirable and is the basis for using atropine in the treatment of excessive muscarinic side effects and cholinergic crisis induced by cholinergic overdose.
MANAGEMENT: Patients receiving long-term therapy with anticholinergic agents should be monitored for potentially diminished therapeutic (miotic) response to ophthalmic cholinergic therapy, and dosages adjusted as necessary.
- "Product Information. Pilopine HS (pilocarpine ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
- "Multum Information Services, Inc. Expert Review Panel"
Generic Name: diphenhydramine / phenylephrine
Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime
Synonyms: n.a.
Generic Name: physostigmine ophthalmic
Brand name:
Synonyms: Physostigmine (Ophthalmic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenhydramine and phenylephrine-Isopto Fenicol
- Diphenhydramine and phenylephrine-Isopto Homatropine
- Diphenhydramine and phenylephrine-Isopto Homatropine Ophthalmic Solution
- Diphenhydramine and phenylephrine-Isopto Hyoscine Ophthalmic Solution
- Diphenhydramine and phenylephrine-Isordil
- Diphenhydramine and phenylephrine-Isordil Titradose
- Isopto Eserine-Diphenhydramine and Phenylephrine Liquid, Solution, and Syrup
- Isopto Eserine-Diphenhydramine and Phenylephrine Oral Strips
- Isopto Eserine-Diphenhydramine Capsules
- Isopto Eserine-Diphenhydramine Capsules and Tablets
- Isopto Eserine-Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets
- Isopto Eserine-Diphenhydramine Elixir, Liquid, and Syrup