Diphenhydramine and phenylephrine and Reglan
Determining the interaction of Diphenhydramine and phenylephrine and Reglan and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:DiphenhydrAMINE may reduce the effects of metoclopramide. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor
Professional:GENERALLY AVOID: Anticholinergic agents and other agents with significant anticholinergic activity (e.g., clozapine, class IA antiarrhythmics especially disopyramide) may antagonize the pharmacologic effects of gastrointestinal prokinetic agents. Gastrokinetic drugs such as domperidone and metoclopramide increase gastrointestinal motility by blocking peripheral dopamine receptors. Anticholinergic agents could negate this action.
MANAGEMENT: Concomitant use of gastrointestinal prokinetic agents with anticholinergic agents should be avoided, if possible.
- "Product Information. Reglan (metoclopramide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
- "Product Information. Motilium (domperidone)." Janssen-Ortho Inc, Toronto, ON.
Generic Name: diphenhydramine / phenylephrine
Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenhydramine and phenylephrine-Reglan (Metoclopramide Injection Solution)
- Diphenhydramine and phenylephrine-Reglan (Metoclopramide Tablets)
- Diphenhydramine and phenylephrine-Reglan Intravenous
- Diphenhydramine and phenylephrine-Reglan Tablets
- Diphenhydramine and phenylephrine-Regonol
- Diphenhydramine and phenylephrine-Regorafenib
- Reglan-Diphenhydramine and Phenylephrine Liquid, Solution, and Syrup
- Reglan-Diphenhydramine and Phenylephrine Oral Strips
- Reglan-Diphenhydramine Capsules
- Reglan-Diphenhydramine Capsules and Tablets
- Reglan-Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets
- Reglan-Diphenhydramine Elixir, Liquid, and Syrup