Diphenhydramine and Phenylephrine Oral Strips and Methyldopa Oral, Intravenous
Determining the interaction of Diphenhydramine and Phenylephrine Oral Strips and Methyldopa Oral, Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenylephrine together with methyldopa may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited data suggest that methyldopa and other sympatholytics may increase or prolong the pressor effect of sympathomimetics. Hypertension may result. Data exist for phenylpropanolamine and norepinephrine.
MANAGEMENT: If these drugs must be coadministered, blood pressure should be closely monitored. Discontinuation of the sympathomimetic may be necessary if hypertension develops.
- McLaren EH "Severe hypertension produced by interaction of phenylpropanolamine with methyldopa and oxprenolol." Br Med J 2 (1976): 283-4
- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Generic Name: diphenhydramine / phenylephrine
Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime
Synonyms: Diphenhydramine and phenylephrine
Generic Name: methyldopa
Brand name: Aldomet
Synonyms: Methyldopa
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenhydramine and Phenylephrine Oral Strips-Methyldopa Tablets
- Diphenhydramine and Phenylephrine Oral Strips-Methyldopate
- Diphenhydramine and Phenylephrine Oral Strips-Methyldopate hydrochloride
- Diphenhydramine and Phenylephrine Oral Strips-Methylene Blue
- Diphenhydramine and Phenylephrine Oral Strips-Methylene blue injection
- Diphenhydramine and Phenylephrine Oral Strips-Methylene blue Oral, Intravenous
- Methyldopa Oral, Intravenous-Diphenhydramine Capsules
- Methyldopa Oral, Intravenous-Diphenhydramine Capsules and Tablets
- Methyldopa Oral, Intravenous-Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets
- Methyldopa Oral, Intravenous-Diphenhydramine Elixir, Liquid, and Syrup
- Methyldopa Oral, Intravenous-Diphenhydramine Hydrochloride
- Methyldopa Oral, Intravenous-Diphenhydramine Injection