Diphenhydramine and Phenylephrine Oral Strips and Pitolisant Hydrochloride
Determining the interaction of Diphenhydramine and Phenylephrine Oral Strips and Pitolisant Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.
MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: diphenhydramine / phenylephrine
Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime
Synonyms: Diphenhydramine and phenylephrine
Generic Name: pitolisant
Brand name: Wakix
Synonyms: Pitolisant
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenhydramine and Phenylephrine Oral Strips-Pitressin
- Diphenhydramine and Phenylephrine Oral Strips-Pitressin Injection
- Diphenhydramine and Phenylephrine Oral Strips-Pitressin Synthetic
- Diphenhydramine and Phenylephrine Oral Strips-Placidyl
- Diphenhydramine and Phenylephrine Oral Strips-Plan B
- Diphenhydramine and Phenylephrine Oral Strips-Plan B One-Step
- Pitolisant Hydrochloride-Diphenhydramine Capsules
- Pitolisant Hydrochloride-Diphenhydramine Capsules and Tablets
- Pitolisant Hydrochloride-Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets
- Pitolisant Hydrochloride-Diphenhydramine Elixir, Liquid, and Syrup
- Pitolisant Hydrochloride-Diphenhydramine Hydrochloride
- Pitolisant Hydrochloride-Diphenhydramine Injection