Diphenoxylate and atropine and Ex-Lax Milk of Magnesia
Determining the interaction of Diphenoxylate and atropine and Ex-Lax Milk of Magnesia and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using atropine together with magnesium hydroxide can decrease the effects of atropine. Magnesium hydroxide should be separated from oral atropine by 3 to 4 hours. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Concurrent administration of antacids or adsorbent antidiarrheal agents may decrease the oral bioavailability of atropine.
MANAGEMENT: Doses of antacids or adsorbent antidiarrheals should be separated from oral atropine by 3 to 4 hours.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine
Generic Name: magnesium hydroxide
Brand name: Ex-Lax Milk of Magnesia, Milk of Magnesia, Pedia-Lax Chewable, Phillips Milk of Magnesia, Dulcolax Milk of Magnesia, Concentrated Phillips Milk of Magnesia
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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