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Diphenoxylate and atropine and Parnate

Determining the interaction of Diphenoxylate and atropine and Parnate and the possibility of their joint administration.

Check result:
Diphenoxylate and atropine <> Parnate
Relevance: 11.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Monoamine oxidase inhibitors and anticholinergic agents may have additive anticholinergic and/or CNS-depressant effects. The clinical significance is unknown.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Multum Information Services, Inc. Expert Review Panel"
Diphenoxylate and atropine

Generic Name: atropine / diphenoxylate

Brand name: Lomotil, Lonox, Lomocot, Vi-Atro

Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine

Parnate

Generic Name: tranylcypromine

Brand name: Parnate

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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