Diphenoxylate and Atropine Oral Solution and Hydromorphone Extended-Release Tablets
Determining the interaction of Diphenoxylate and Atropine Oral Solution and Hydromorphone Extended-Release Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using HYDROmorphone together with atropine can increase the effects of either medication. This can commonly cause dizziness, drowsiness, difficulty concentrating, dry mouth, abdominal cramping, and constipation. Some people may also experience some impairment in thinking and judgment. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of narcotic analgesics with anticholinergic agents may result in additive central nervous system (CNS) and gastrointestinal (GI) adverse effects, and increase the risk of severe constipation or paralytic ileus and CNS depression.
MANAGEMENT: If concomitant use cannot be avoided, patients should be monitored for potentially excessive or prolonged CNS depression and constipation. Ambulatory patients should be counseled to avoid activities requiring mental alertness until they know how these agents affect them.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine
Generic Name: hydromorphone
Brand name: Dilaudid, Exalgo, Hydrostat IR, Dilaudid-HP
Synonyms: Hydromorphone, HYDROmorphone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenoxylate and Atropine Oral Solution-Hydromorphone Hydrochloride
- Diphenoxylate and Atropine Oral Solution-Hydromorphone injection
- Diphenoxylate and Atropine Oral Solution-Hydromorphone Liquid
- Diphenoxylate and Atropine Oral Solution-Hydromorphone rectal
- Diphenoxylate and Atropine Oral Solution-Hydromorphone Suppository
- Diphenoxylate and Atropine Oral Solution-Hydromorphone Tablets
- Hydromorphone Extended-Release Tablets-Diphenoxylate and Atropine Solution
- Hydromorphone Extended-Release Tablets-Diphenoxylate and Atropine Tablets
- Hydromorphone Extended-Release Tablets-Diphenoxylate Hydrochloride
- Hydromorphone Extended-Release Tablets-Diphtheria & Tetanus Tox, Acell Pertussis, Hep B (Recomb), Polio Vacc
- Hydromorphone Extended-Release Tablets-Diphtheria & Tetanus Tox/Acell Pertussis/Polio Vacc
- Hydromorphone Extended-Release Tablets-Diphtheria and Tetanus Toxoids