Diphenoxylate and Atropine Tablets and Ipratropium Nasal 0.03
Determining the interaction of Diphenoxylate and Atropine Tablets and Ipratropium Nasal 0.03 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Theoretically, the potential exists for additive anticholinergic effects such as mydriasis, blurred vision, heat intolerance, fever, dry mouth, tachycardia, urinary retention, constipation, and glaucoma (new onset or exacerbation) when ipratropium nasal spray is used with other agents that possess anticholinergic properties (e.g., antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide). However, due to the poor systemic absorption of ipratropium when administered nasally, the interaction would be unlikely at regularly recommended dosages.
- "Product Information. Atrovent nasal spray (ipratropium nasal)." Boehringer-Ingelheim, Ridgefield, CT.
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine
Generic Name: ipratropium nasal
Brand name: Atrovent Nasal
Synonyms: Ipratropium nasal, Ipratropium (Nasal)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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