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Diphenoxylate and Atropine Tablets and Neut

Determining the interaction of Diphenoxylate and Atropine Tablets and Neut and the possibility of their joint administration.

Check result:
Diphenoxylate and Atropine Tablets <> Neut
Relevance: 01.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using atropine together with sodium bicarbonate can decrease the effects of atropine. Sodium bicarbonate should be separated from oral atropine by 3 to 4 hours. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Concurrent administration of antacids or adsorbent antidiarrheal agents may decrease the oral bioavailability of atropine.

MANAGEMENT: Doses of antacids or adsorbent antidiarrheals should be separated from oral atropine by 3 to 4 hours.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Diphenoxylate and Atropine Tablets

Generic Name: atropine / diphenoxylate

Brand name: Lomotil, Lonox, Lomocot, Vi-Atro

Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine

Neut

Generic Name: sodium bicarbonate

Brand name: Neut

Synonyms: Neut Injection

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle