Diphenoxylate Hydrochloride and Magonate (Magnesium Carbonate)
Determining the interaction of Diphenoxylate Hydrochloride and Magonate (Magnesium Carbonate) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using atropine together with magnesium carbonate can decrease the effects of atropine. Magnesium carbonate should be separated from oral atropine by 3 to 4 hours. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Concurrent administration of antacids or adsorbent antidiarrheal agents may decrease the oral bioavailability of atropine.
MANAGEMENT: Doses of antacids or adsorbent antidiarrheals should be separated from oral atropine by 3 to 4 hours.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: atropine / diphenoxylate
Brand name: Lomotil, Lonox, Lomocot, Vi-Atro
Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine
Generic Name: magnesium carbonate
Brand name: Magonate
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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