Disopyramide Phosphate and Rheumatrex Dose Pack

• Generic Name: disopyramide
• Dosage Forms: n.a.
• Other Brand Names: Norpace, Norpace CR

Precise role in antiarrhythmic therapy has not been established. Some experts recommend that disopyramide be reserved for use as an alternative drug when lidocaine, quinidine, or procainamide is ineffective or adverse effects of these drugs are intolerable.

Limited information is available on combination therapy with other antiarrhythmic drugs such as lidocaine, quinidine, or procainamide to treat or prevent serious, refractory arrhythmias.

Suppression and prevention of recurrent life-threatening ventricular arrhythmias (e.g., sustained VT). (See Boxed Warning.)

Because of disopyramide’s arrhythmogenic potential and lack of evidence for improved survival for class I antiarrhythmic agents, use for less severe arrhythmias is not recommended.

Avoid treatment of asymptomatic VPCs.

Has been used to convert atrial fibrillation, atrial flutter, and paroxysmal atrial tachycardia to normal sinus rhythm. However, other antiarrhythmic drugs (e.g., dofetilide, flecainide, ibutilide, propafenone, amiodarone) are preferred.

• Generic Name: methotrexate
• Dosage Forms: tablet
• Other Brand Names: Rheumatrex Dose Pack, Trexall, Xatmep, Otrexup, Rasuvo, Methotrexate Sodium, Preservative Free

Rheumatrex Dose Pack interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Rheumatrex Dose Pack is used to treat certain types of cancer of the breast, skin, head and neck, or lung. This medicine is also used to treat severe psoriasis and rheumatoid arthritis.

Rheumatrex Dose Pack is usually given after other medications have been tried without successful treatment of symptoms.

Rheumatrex Dose Pack may also be used for purposes not listed in this medication guide.