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Disopyramide Sustained-Release Capsules and Milrinone Dextrose

Determining the interaction of Disopyramide Sustained-Release Capsules and Milrinone Dextrose and the possibility of their joint administration.

Check result:
Disopyramide Sustained-Release Capsules <> Milrinone Dextrose
Relevance: 14.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using disopyramide and milrinone together may lower your blood pressure. This can cause a slow heartbeat, headaches, dizziness, or feeling like you might pass out. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: According to the manufacturer, there has been one case report of excessive hypotension when inamrinone was used concurrently with disopyramide. No other detail is provided.

MANAGEMENT: Until further data are available, it may be appropriate to closely monitor hemodynamic status during concomitant administration of these drugs. The same precaution may be applicable to milrinone based on its structural and pharmacologic similarities to inamrinone.

References
  • "Product Information. Inocor (inamrinone)." Sanofi Winthrop Pharmaceuticals, New York, NY.
Disopyramide Sustained-Release Capsules

Generic Name: disopyramide

Brand name: Norpace, Norpace CR

Synonyms: Disopyramide

Milrinone Dextrose

Generic Name: milrinone

Brand name: Primacor, Primacor IV.

Synonyms: Milrinone

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.