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Disulfiram and Trilafon

Determining the interaction of Disulfiram and Trilafon and the possibility of their joint administration.

Check result:

Disulfiram <> Trilafon

Relevance: 08.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Disulfiram may reduce the therapeutic action of orally administered perphenazine. The mechanism is unknown. A change to a parenteral form of perphenazine or to another agent may be necessary.

References

Hansen LB, Larsen N-E "Metabolic interaction between perphenazine and disulfiram." Lancet 2 (1982): 1472

Disulfiram

Generic Name: disulfiram

Brand name: Antabuse

Synonyms: n.a.

What is Disulfiram?

Trilafon

Generic Name: perphenazine

Brand name: Trilafon

Synonyms: n.a.

What is Trilafon?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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