Divalproex Delayed Release Tablets and Nymalize (Nimodipine Oral Solution)
Determining the interaction of Divalproex Delayed Release Tablets and Nymalize (Nimodipine Oral Solution) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Valproic acid and its derivatives may increase the effects of nimodipine by decreasing first-pass metabolism and increasing bioavailability. Patients who must take both drugs should be carefully monitored for increased nimodipine effect.
- Tartara A, Galimberti CA, Manni R, et al "Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients." Br J Clin Pharmacol 32 (1991): 335-40
- Tartara A, Galimberti CA, Manni R, et al "Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients." Br J Clin Pharmacol 32 (1991): 335-40
Generic Name: divalproex sodium
Brand name: Depakote ER, Depakote Sprinkles, Depakote, Depakene, Depacon
Synonyms: Divalproex sodium, Divalproex
Generic Name: nimodipine
Brand name: Nymalize, Nimotop
Synonyms: Nymalize
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Divalproex Delayed Release Tablets-NyQuil
- Divalproex Delayed Release Tablets-Nyquil Cold & Flu
- Divalproex Delayed Release Tablets-NyQuil Cold & Flu (Alcohol Free)
- Divalproex Delayed Release Tablets-NyQuil Cough
- Divalproex Delayed Release Tablets-NyQuil D
- Divalproex Delayed Release Tablets-NyQuil Multi-Symptom
- Nymalize (Nimodipine Oral Solution)-Divalproex Extended Release
- Nymalize (Nimodipine Oral Solution)-Divalproex Long-Acting Tablets
- Nymalize (Nimodipine Oral Solution)-Divalproex sodium
- Nymalize (Nimodipine Oral Solution)-Divalproex Sprinkle
- Nymalize (Nimodipine Oral Solution)-Divalproex Sprinkle Capsules
- Nymalize (Nimodipine Oral Solution)-Divigel