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Dolobid and Excedrin Tension Headache Caplet

Determining the interaction of Dolobid and Excedrin Tension Headache Caplet and the possibility of their joint administration.

Check result:
Dolobid <> Excedrin Tension Headache Caplet
Relevance: 08.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Acetaminophen serum concentrations may be elevated by as much as 50% during concomitant therapy with diflunisal in normal subjects. The clinical significance of this finding is unknown. Because elevated acetaminophen levels are associated with hepatotoxicity, the manufacturer recommends caution when this combination is used.

References
  • "Product Information. Dolobid (diflunisal)." Merck & Co, Inc, West Point, PA.
Dolobid

Generic Name: diflunisal

Brand name: Dolobid

Synonyms: n.a.

Excedrin Tension Headache Caplet

Generic Name: acetaminophen / caffeine

Brand name: Excedrin Mild Headache, Excedrin Quick Tab Peppermint, Excedrin Quick Tab Spearmint, Excedrin Tension Headache, Excedrin Tension Headache Caplet, Excedrin Tension Headache Express Gels, Excedrin Tension Headache Geltab, Valorin Extra, Excedrin Tension Headache Express

Synonyms: Excedrin Tension Headache

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle