Dolutegravir Sodium and Rilpivirine Hydrochloride and Marvelon 21

• Generic Name: dolutegravir / rilpivirine
• Dosage Forms: n.a.
• Other Brand Names: Juluca

Treatment of HIV-1 infection in certain antiretroviral-experienced (previously treated) adults.

Use to replace the current regimen only in antiretroviral-experienced adults who are virologically suppressed (i.e., plasma HIV-1 RNA levels <50 copies/mL) on a stable antiretroviral regimen for ≥6 months, have no known history of treatment failure, and are infected with HIV-1 with no known substitutions associated with resistance to dolutegravir or rilpivirine.

Used alone as a complete regimen for treatment of HIV-1 infection in these antiretroviral-experienced adults; manufacturer states concomitant use with other antiretrovirals not recommended.

• Generic Name: desogestrel / ethinyl estradiol
• Dosage Forms: n.a.
• Other Brand Names: Azurette, Cyclessa, Desogen, Isibloom, Kariva, Mircette, Reclipsen, Cyred

Desogestrel and ethinyl estradiol combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, desogestrel and ethinyl estradiol, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization (pregnancy) is prevented.

No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.

This medicine does not prevent HIV infection or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.

This medicine is available only with your doctor's prescription.