Dolutegravir Sodium and Rilpivirine Hydrochloride and Phenazopyridine Hydrochloride

• Generic Name: dolutegravir / rilpivirine
• Dosage Forms: n.a.
• Other Brand Names: Juluca

Treatment of HIV-1 infection in certain antiretroviral-experienced (previously treated) adults.

Use to replace the current regimen only in antiretroviral-experienced adults who are virologically suppressed (i.e., plasma HIV-1 RNA levels <50 copies/mL) on a stable antiretroviral regimen for ≥6 months, have no known history of treatment failure, and are infected with HIV-1 with no known substitutions associated with resistance to dolutegravir or rilpivirine.

Used alone as a complete regimen for treatment of HIV-1 infection in these antiretroviral-experienced adults; manufacturer states concomitant use with other antiretrovirals not recommended.

• Generic Name: phenazopyridine
• Dosage Forms: n.a.
• Other Brand Names: AZO Urinary Pain Relief, Azo-Gesic, Azo-Standard, Baridium, Prodium, Pyridium, Re-Azo, Uricalm, Viridium, Eridium, Pyridiate, Urogesic, Phenazo, Urodol, Urinary Analgesic, Uristat, AZO Urinary Pain Relief Max Strength

Symptomatic relief of pain, burning, urgency, frequency, and other discomforts resulting from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters.

Use should not delay definitive diagnosis and treatment of cause; not a substitute for specific surgery or anti-infective therapy.

Used in combination with appropriate anti-infective agents for initial treatment (first 2 days) of uncomplicated urinary tract infections when pain, burning, or urgency relief is needed. However, there is lack of evidence that such combinations provide greater benefit than an anti-infective agent alone after 2 days; continue treatment after 2 days with anti-infective agent alone.

Also may be used for self-medication for the symptomatic relief of minor pain, urgency, frequency, and burning on urination.