Dolutegravir Sodium and Rilpivirine Hydrochloride and Tezacaftor and Ivacaftor

• Generic Name: dolutegravir / rilpivirine
• Dosage Forms: n.a.
• Other Brand Names: Juluca

Treatment of HIV-1 infection in certain antiretroviral-experienced (previously treated) adults.

Use to replace the current regimen only in antiretroviral-experienced adults who are virologically suppressed (i.e., plasma HIV-1 RNA levels <50 copies/mL) on a stable antiretroviral regimen for ≥6 months, have no known history of treatment failure, and are infected with HIV-1 with no known substitutions associated with resistance to dolutegravir or rilpivirine.

Used alone as a complete regimen for treatment of HIV-1 infection in these antiretroviral-experienced adults; manufacturer states concomitant use with other antiretrovirals not recommended.

• Generic Name: ivacaftor / tezacaftor
• Dosage Forms: n.a.
• Other Brand Names: Symdeko, Symdeko 4-Week

• It is used to treat cystic fibrosis.