Dolutegravir Sodium and Rilpivirine Hydrochloride and TL-Hist DM

• Generic Name: dolutegravir / rilpivirine
• Dosage Forms: n.a.
• Other Brand Names: Juluca

Treatment of HIV-1 infection in certain antiretroviral-experienced (previously treated) adults.

Use to replace the current regimen only in antiretroviral-experienced adults who are virologically suppressed (i.e., plasma HIV-1 RNA levels <50 copies/mL) on a stable antiretroviral regimen for ≥6 months, have no known history of treatment failure, and are infected with HIV-1 with no known substitutions associated with resistance to dolutegravir or rilpivirine.

Used alone as a complete regimen for treatment of HIV-1 infection in these antiretroviral-experienced adults; manufacturer states concomitant use with other antiretrovirals not recommended.

• Generic Name: brompheniramine / dextromethorphan / phenylephrine
• Dosage Forms: oral liquid
• Other Brand Names: Alahist DM, BP Allergy DM, Bromatan-DM, Children's Cold & Cough DM, Cold & Cough Childrens, Dimaphen DM, Dimetapp Cold & Cough, Dimetapp DM Cold & Cough, DuraTan DM, Rynex DM, TL-Hist DM, Tussi-Pres B, Dimetapp DM Cold/Cough, Glenmax PEB DM FORTE, Glenmax PEB DM, LoHist-DM, Niva-Hist DM, TGQ 75PEH/4BRM/15DM

Brompheniramine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dextromethorphan, and phenylephrine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

TL-Hist DM will not treat a cough that is caused by smoking, asthma, or emphysema.

TL-Hist DM may also be used for purposes not listed in this medication guide.