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Donepezil ER Tablets and Xenleta (Lefamulin Injection)

Determining the interaction of Donepezil ER Tablets and Xenleta (Lefamulin Injection) and the possibility of their joint administration.

Check result:
Donepezil ER Tablets <> Xenleta (Lefamulin Injection)
Relevance: 27.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Acetylcholinesterase inhibitors may have vagotonic effects on the sinoatrial and atrioventricular nodes, which occasionally manifest as bradycardia or heart block (

Professional:

MONITOR: Acetylcholinesterase inhibitors may have vagotonic effects on the sinoatrial and atrioventricular nodes, which occasionally manifest as bradycardia or heart block (

References
  • "Product Information. Exelon (rivastigmine)" Novartis Pharmaceuticals, East Hanover, NJ.
  • "Product Information. Razadyne (galantamine)." Johnson and Johnson Medical Inc, Arlington, TX.
  • "Product Information. Aricept (donepezil)." Pfizer US Pharmaceuticals, New York, NY.
  • Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
Donepezil ER Tablets

Generic Name: donepezil

Brand name: Aricept, Aricept ODT

Synonyms: Donepezil

Xenleta (Lefamulin Injection)

Generic Name: lefamulin

Brand name: Xenleta

Synonyms: Xenleta, Xenleta (oral/injection)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.