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Dopamine and Dextrose and Vancomycin Intravenous, Injection

Determining the interaction of Dopamine and Dextrose and Vancomycin Intravenous, Injection and the possibility of their joint administration.

Check result:
Dopamine and Dextrose <> Vancomycin Intravenous, Injection
Relevance: 11.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

DOPamine may reduce the blood levels of vancomycin, which may make it less effective in treating infections. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The concomitant administration of parenteral vancomycin with dopamine or dobutamine may reduce the serum levels of vancomycin. Increased cardiac output and renal blood blow by the sympathomimetics enhances the renal clearance of vancomycin.

MANAGEMENT: Therapeutic drug monitoring of vancomycin serum levels is advisable during coadministration.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Dopamine and Dextrose

Generic Name: dopamine

Brand name: Intropin

Synonyms: Dopamine Injection, DOPamine

Vancomycin Intravenous, Injection

Generic Name: vancomycin

Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50

Synonyms: Vancomycin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.