Dopamine Hydrochloride and Lidocaine Hydrochloride
Determining the interaction of Dopamine Hydrochloride and Lidocaine Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that low dose dopamine (2 mcg/kg/min) increases lidocaine dose requirements to maintain epidural anesthesia by as much as 45% without a significant change in plasma lidocaine concentrations. The mechanism may be related to enhanced hepatic lidocaine elimination. Clinical monitoring of anesthetic response is recommended and lidocaine dosage adjustments may be necessary.
- Sprung J, Bourke DL, Schoenwald PK, Whalley D, Gottlieb A, Mascha EJ, Kapural L "Small-dose dopamine increases epidural lidocaine requirements during peripheral vascular surgery in elderly patients." Anesth Analg 90 (2000): 388-92
Generic Name: dopamine
Brand name: Intropin
Synonyms: Dopamine Injection, DOPamine
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: Lidocaine injection, Lidocaine (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dopamine Hydrochloride-Lidocaine Hydrochloride (Local)
- Dopamine Hydrochloride-Lidocaine injection
- Dopamine Hydrochloride-Lidocaine Injection Solution (Anesthetic)
- Dopamine Hydrochloride-Lidocaine Intradermal
- Dopamine Hydrochloride-Lidocaine Intradermal Injection
- Dopamine Hydrochloride-Lidocaine IV Solution
- Lidocaine Hydrochloride-Dopamine injection
- Lidocaine Hydrochloride-Dopamine Injection, Concentrate
- Lidocaine Hydrochloride-Dopram
- Lidocaine Hydrochloride-Doptelet
- Lidocaine Hydrochloride-Doral
- Lidocaine Hydrochloride-Doral Tablets