Dorzolamide and Timolol Ophthalmic Solution and Sufentanil Sublingual Tablets
Determining the interaction of Dorzolamide and Timolol Ophthalmic Solution and Sufentanil Sublingual Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using SUFentanil together with timolol ophthalmic may lead to increased side effects. This can cause decreased heart rate and blood pressure. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: In patients receiving chronic beta-blocker therapy, the use of sufentanil may lead to a higher degree of bradycardia and hypotension. One study has shown that induction and maintenance of anesthesia requires lower doses of sufentanil in patients receiving beta-blockers.
MANAGEMENT: Patients should be carefully observed for clinically significant alterations in hemodynamics.
- Thomson IR, MacAdams CL, Hudson RJ, Rosenbloom M "Drug interactions with sufentanil: hemodynamic effects of premedication and muscle relaxants." Anesthesiology 76 (1992): 922-9
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- "Product Information. Sufenta (sufentanil)." Janssen Pharmaceutica, Titusville, NJ.
Generic Name: dorzolamide / timolol ophthalmic
Brand name: Cosopt, Cosopt PF
Synonyms: Dorzolamide and timolol ophthalmic, Dorzolamide and Timolol
Generic Name: sufentanil
Brand name: Dsuvia
Synonyms: SUFentanil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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