Dorzolamide Hydrochloride and Poly-Tussin AC

• Generic Name: dorzolamide ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Trusopt

Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Fixed-combination preparation containing dorzolamide and timolol (Cosopt) used topically to reduce elevated IOP in patients with open-angle glaucoma or ocular hypertension who have not responded adequately (i.e., failed to achieve target IOP as determined after multiple measurements over time) to a topical β-adrenergic blocking agent. Fixed-combination preparation associated with slightly smaller decrease in IOP than combination therapy with dorzolamide (administered 3 times daily) and timolol (administered twice daily).

A first-line “add-on” agent when more than one drug is needed. Add-on therapy with dorzolamide to existing timolol therapy is as effective and better tolerated than add-on therapy with pilocarpine.

Safety and efficacy not established for the treatment of acute angle-closure glaucoma.

Used prophylactically before neodymium yttrium aluminum garnet (Nd:YAG) laser posterior capsulotomy.

Administration of 1 drop (20 µL) of dorzolamide 2% 1 hour prior to capsulotomy is more effective in preventing postoperative increases in IOP than placebo and as effective as oral acetazolamide 125 mg administered 1 hour prior to the procedure.

• Generic Name: brompheniramine / codeine / phenylephrine
• Dosage Forms: n.a.
• Other Brand Names: M-End PE, Poly-Tussin AC, TL-Hist CD

Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Codeine is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Poly-Tussin AC is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

Poly-Tussin AC will not treat a cough that is caused by smoking, asthma, or emphysema.

Poly-Tussin AC may also be used for purposes not listed in this medication guide.