Doxazosin Extended-Release Tablets and Sudafed PSE
Determining the interaction of Doxazosin Extended-Release Tablets and Sudafed PSE and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using doxazosin together with pseudoephedrine may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Sympathomimetic agents, such as pseudoephedrine, may antagonize the effects of antihypertensives that interfere with sympathetic activity, such as alpha- and beta-adrenergic blocking agents. In contrast, alpha- and beta-blockers may diminish the vasoconstrictive effects of sympathomimetics. The mechanism of this interaction has not been reported, but may involve competitive inhibition at the adrenergic receptor. Severe hypertension may occur in patients receiving beta-blockers.
MANAGEMENT: Caution and close monitoring of blood pressure is recommended if pseudoephedrine is administered with these antihypertensives. Discontinuation of the sympathomimetic may be necessary if hypertension develops.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Generic Name: doxazosin
Brand name: Cardura, Cardura XL, Doxadura, Cascor, Carduran
Synonyms: Doxazosin
Generic Name: naproxen / pseudoephedrine
Brand name: Aleve Cold and Sinus, Aleve Sinus & Headache, Aleve-D Sinus & Cold, Sudafed PSE, Aleve-D Cold and Sinus, Sudafed Sinus & Pain 12 Hour, Sinus & Cold-D, Sudafed Sinus 12 Hour Pressure + Pain, Aleve-D Sinus & Headache, Sudafed 12 Hour Pressure + Pain
Synonyms: Naproxen and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Doxazosin Extended-Release Tablets-Sudafed Sinus Nighttime
- Doxazosin Extended-Release Tablets-Sudal 12 Tannate Chewable
- Doxazosin Extended-Release Tablets-Sudatex DM
- Doxazosin Extended-Release Tablets-SudoGest
- Doxazosin Extended-Release Tablets-SudoGest 12 Hour
- Doxazosin Extended-Release Tablets-Sudogest PE
- Sudafed PSE-Doxazosin Mesylate
- Sudafed PSE-Doxazosin Tablets
- Sudafed PSE-Doxepin
- Sudafed PSE-Doxepin (Systemic)
- Sudafed PSE-Doxepin Capsules
- Sudafed PSE-Doxepin Cream