Doxepin and Lomitapide Mesylate

• Generic Name: doxepin
• Dosage Forms: n.a.
• Other Brand Names: Sinequan, Sinequan, Silenor

Doxepin is used to treat anxiety or depression. It is also used to treat insomnia (trouble with sleeping).

Doxepin is a tricyclic antidepressant (TCA). It works on the central nervous system (CNS) to increase levels of certain chemicals in the brain.

Doxepin is available only with your doctor's prescription.

• Generic Name: lomitapide
• Dosage Forms: n.a.
• Other Brand Names: Juxtapid

Adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available, to reduce LDL-cholesterol, total cholesterol, apolipoprotein B (apo B), and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Effects on cardiovascular morbidity and mortality not established.