Doxepin Hydrochloride topical and Guanfacine
Determining the interaction of Doxepin Hydrochloride topical and Guanfacine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using doxepin topical together with guanFACINE can decrease the effects of guanFACINE. Talk with your doctor before using doxepin topical and guanFACINE together. You may need a dose adjustment or need your blood pressure checked more often if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: One case report suggests that tricyclic antidepressants may decrease the antihypertensive effect of guanfacine. The mechanism is unknown.
MANAGEMENT: The patient's blood pressure should be monitored during concomitant therapy and after discontinuation or dose change of the antidepressant. An alternative antihypertensive (e.g., beta adrenergic blocking agent, diuretic) may be considered.
- Buckley M, Feely J "Antagonism of antihypertensive effect of guanfacine by tricyclic antidepressants." Lancet 337 (1991): 1173-4
Generic Name: doxepin topical
Brand name: Prudoxin, Zonalon
Synonyms: Doxepin topical, Doxepin (Topical)
Generic Name: guanfacine
Brand name: Intuniv, Tenex
Synonyms: GuanFACINE
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Doxepin Hydrochloride topical-Guanfacine ER
- Doxepin Hydrochloride topical-Guanfacine Extended-Release Tablets
- Doxepin Hydrochloride topical-Guanfacine Tablets
- Doxepin Hydrochloride topical-Guanidine
- Doxepin Hydrochloride topical-Guar Gum
- Doxepin Hydrochloride topical-Guiadrine DX
- Guanfacine-Doxepin Oral Concentrate
- Guanfacine-Doxepin Oral Solution Concentrate
- Guanfacine-Doxepin Sinequan
- Guanfacine-Doxepin Tablets
- Guanfacine-Doxepin topical
- Guanfacine-Doxercalciferol