Doxepin (Systemic) and Ketamine Intramuscular, Intravenous
Determining the interaction of Doxepin (Systemic) and Ketamine Intramuscular, Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before getting anesthesia with ketamine, tell your doctor if you are taking doxepin. Using these medications together may cause low blood pressure and irregular heart rhythm. In some cases, your doctor may want you to stop taking doxepin for 10 to 14 days before you undergo surgery. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of pancuronium may increase the risk of tachyarrhythmias. Enflurane may also increase the risk of seizures when given to patients who have been taking tricyclic antidepressants.
MANAGEMENT: Close monitoring is recommended when these drugs are used together.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: doxepin
Brand name: Sinequan, Sinequan, Silenor
Synonyms: Doxepin (Sinequan)
Generic Name: ketamine
Brand name: Ketalar
Synonyms: Ketamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Doxepin (Systemic)-Ketek
- Doxepin (Systemic)-Ketek Pak
- Doxepin (Systemic)-Ketocon
- Doxepin (Systemic)-Ketoconazole
- Doxepin (Systemic)-Ketoconazole (Systemic)
- Doxepin (Systemic)-Ketoconazole and Hydrocortisone
- Ketamine Intramuscular, Intravenous-Doxepin Capsules
- Ketamine Intramuscular, Intravenous-Doxepin Cream
- Ketamine Intramuscular, Intravenous-Doxepin Hydrochloride
- Ketamine Intramuscular, Intravenous-Doxepin Hydrochloride topical
- Ketamine Intramuscular, Intravenous-Doxepin Oral Concentrate
- Ketamine Intramuscular, Intravenous-Doxepin Oral Solution Concentrate