Doxercalciferol and Vortioxetine Hydrobromide

• Generic Name: doxercalciferol
• Dosage Forms: n.a.
• Other Brand Names: Hectorol

Treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) undergoing dialysis.

Oral doxercalciferol also used in the treatment of secondary hyperparathyroidism in patients with stage 3 or 4 CKD who do not yet require maintenance dialysis (predialysis patients).

Suppresses elevated serum or plasma parathyroid hormone (PTH) concentrations associated with secondary hyperparathyroidism in patients with CKD. Deficient production of biologically active vitamin D metabolites leads to secondary hyperparathyroidism, which contributes to the development of metabolic bone disease.

• Generic Name: vortioxetine
• Dosage Forms: n.a.
• Other Brand Names: Trintellix, Brintellix

Treatment of major depressive disorder in adults.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, tricyclic antidepressants (TCAs), MAO inhibitors, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on the following factors: patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; specific properties of the medication (e.g., half-life, actions on CYP isoenzymes, other drug interactions); and cost. For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal.