Doxercalciferol Injection and Sucroferric oxyhydroxide

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Sucroferric oxyhydroxide may interfere with the absorption of oral vitamin D products and reduce their effectiveness. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Coadministration with sucroferric oxyhydroxide may reduce the oral bioavailability of vitamin D analogs. The proposed mechanism involves nonspecific adsorption to the ferric ion component of sucroferric oxyhydroxide, resulting in an insoluble complex that is poorly absorbed from the gastrointestinal tract. According to the product labeling for sucroferric oxyhydroxide, an in vitro interaction with paricalcitol was observed when studied in aqueous solutions that mimic the physico-chemical conditions of the gastrointestinal tract.

MANAGEMENT: Oral formulations of vitamin D analogs should not be prescribed with sucroferric oxyhydroxide.

Doxercalciferol Injection

Generic Name: doxercalciferol

Brand name: Hectorol

Synonyms: Doxercalciferol (oral/injection), Doxercalciferol

What is Doxercalciferol Injection?

Sucroferric oxyhydroxide

Generic Name: sucroferric oxyhydroxide

Brand name: Velphoro

Synonyms: Sucroferric Oxyhydroxide

What is Sucroferric oxyhydroxide?