Doxy 100 and Potassium citrate
Determining the interaction of Doxy 100 and Potassium citrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using potassium citrate together with doxycycline may decrease the effects of doxycycline. Administration of potassium citrate and doxycycline should be separated by three to four hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Alkalinization of the urine may decrease the plasma concentration of some tetracyclines. The mechanism is not completely understood, but may involve increased renal elimination of tetracyclines when the urine becomes alkalinized. Information is available for doxycycline, tetracycline, and sodium bicarbonate only.
MANAGEMENT: If these drugs must be used together, an alternating dosing schedule is recommended (three to four hours apart).
- Elliott GR "Sodium bicarbonate and oral tetracycline." Clin Pharmacol Ther 13 (1972): 459
- Jaffe JM, Colaizzi JI, Poust RI, McDonald RH Jr "Effect of altered urinary pH on tetracycline and doxycycline excretion in humans." J Pharmacokinet Biopharm 1 (1973): 267-82
- Jaffe JM, Poust RI, Feld SL, Colaizzi JL "Influence of repetitive dosing and altered urinary pH on doxycycline excretion in humans." J Pharm Sci 63 (1974): 1256-60
Generic Name: doxycycline
Brand name: Doxy 100, Acticlate, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, Monodox, Morgidox, Oraxyl, TargaDOX, Vibramycin, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Oracea, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, TargaDOX
Synonyms: n.a.
Generic Name: potassium citrate
Brand name: Urocit-K
Synonyms: Potassium, Potassium Citrate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Doxy 100-Potassium Citrate and Citric Acid Powder Pack
- Doxy 100-Potassium Citrate and Citric Acid Solution
- Doxy 100-Potassium Citrate-Citric Acid Crystals
- Doxy 100-Potassium Citrate-Sodium Citrate-Citric Acid Solution
- Doxy 100-Potassium gluconate
- Doxy 100-Potassium Gluconate Capsules and Tablets
- Potassium citrate-Doxycycline
- Potassium citrate-Doxycycline Calcium
- Potassium citrate-Doxycycline Capsules (Rosacea)
- Potassium citrate-Doxycycline Capsules with Omega-3 and Vitamin E Capsules
- Potassium citrate-Doxycycline Delayed Release Capsule
- Potassium citrate-Doxycycline Delayed-Release Tablets