Doxycycline Capsules (Rosacea) and Omeprazole and Sodium Bicarbonate Capsules
Determining the interaction of Doxycycline Capsules (Rosacea) and Omeprazole and Sodium Bicarbonate Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sodium bicarbonate together with doxycycline may decrease the effects of doxycycline. Administration of sodium bicarbonate and doxycycline should be separated by three to four hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Alkalinization of the urine may decrease the plasma concentration of some tetracyclines. The mechanism is not completely understood, but may involve increased renal elimination of tetracyclines when the urine becomes alkalinized. Information is available for doxycycline, tetracycline, and sodium bicarbonate only.
MANAGEMENT: If these drugs must be used together, an alternating dosing schedule is recommended (three to four hours apart).
- Elliott GR "Sodium bicarbonate and oral tetracycline." Clin Pharmacol Ther 13 (1972): 459
- Jaffe JM, Colaizzi JI, Poust RI, McDonald RH Jr "Effect of altered urinary pH on tetracycline and doxycycline excretion in humans." J Pharmacokinet Biopharm 1 (1973): 267-82
- Jaffe JM, Poust RI, Feld SL, Colaizzi JL "Influence of repetitive dosing and altered urinary pH on doxycycline excretion in humans." J Pharm Sci 63 (1974): 1256-60
Generic Name: doxycycline
Brand name: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, TargaDOX, Vibramycin, Doxy 100, TargaDOX
Synonyms: Doxycycline
Generic Name: omeprazole / sodium bicarbonate
Brand name: Zegerid, Zegerid OTC
Synonyms: Omeprazole and sodium bicarbonate, Omeprazole and Sodium Bicarbonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Doxycycline Capsules (Rosacea)-Omeprazole and Sodium Bicarbonate Powder Packets
- Doxycycline Capsules (Rosacea)-Omeprazole Delayed-Release Capsules
- Doxycycline Capsules (Rosacea)-Omeprazole Delayed-Release Capsules and Tablets (OTC)
- Doxycycline Capsules (Rosacea)-Omeprazole Orally-Disintegrating Tablets
- Doxycycline Capsules (Rosacea)-Omeprazole Powder for Oral Suspension
- Doxycycline Capsules (Rosacea)-Omeprazole Tablets
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Capsules with Omega-3 and Vitamin E Capsules
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Delayed Release Capsule
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Delayed-Release Tablets
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Hyclate
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Hyclate Delayed Release
- Omeprazole and Sodium Bicarbonate Capsules-Doxycycline Hyclate eent