Doxylamine Succinate and ONZETRA Xsail

• Generic Name: doxylamine
• Dosage Forms: n.a.
• Other Brand Names: Unisom, Nytol Maximum Strength, Aldex AN, Nitetime Sleep-Aid, Sleep Aid

Self-medication for short-term management of insomnia, particularly in individuals who have difficulty falling asleep.

Safety and efficacy not fully established; however, FDA states that, pending further accumulation of data, doxylamine-containing nighttime sleep aids approved for this use may continue to be marketed in the US.

Used in fixed combination with pyridoxine for treatment of nausea and vomiting of pregnancy in women not responding to conservative management.

Not studied in patients with hyperemesis gravidarum.

Temporary relief of rhinorrhea, sneezing, lacrimation, itching eyes, or oronasopharyngeal itching associated with allergic rhinitis (e.g., hay fever) or other upper respiratory allergies.

• Generic Name: sumatriptan
• Dosage Forms: nasal powder
• Other Brand Names: ONZETRA Xsail, Alsuma, Imitrex, Imitrex STATdose, Imitrex Statdose Refill, Sumavel DosePro, Zembrace SymTouch, SUMAtriptan Succinate Syringe, Imitrex<, Tosymra, Zecuity

• It is used to treat migraine headaches.