Doxylamine Succinate and Timolol eent

• Generic Name: doxylamine
• Dosage Forms: n.a.
• Other Brand Names: Unisom, Nytol Maximum Strength, Aldex AN, Nitetime Sleep-Aid, Sleep Aid

Self-medication for short-term management of insomnia, particularly in individuals who have difficulty falling asleep.

Safety and efficacy not fully established; however, FDA states that, pending further accumulation of data, doxylamine-containing nighttime sleep aids approved for this use may continue to be marketed in the US.

Used in fixed combination with pyridoxine for treatment of nausea and vomiting of pregnancy in women not responding to conservative management.

Not studied in patients with hyperemesis gravidarum.

Temporary relief of rhinorrhea, sneezing, lacrimation, itching eyes, or oronasopharyngeal itching associated with allergic rhinitis (e.g., hay fever) or other upper respiratory allergies.

• Generic Name: timolol ophthalmic
• Dosage Forms: n.a.
• Other Brand Names: Betimol, Istalol, Timoptic Ocudose, Timoptic Ocumeter, Timoptic Ocumeter Plus, Timoptic-XE, Timoptic

Reduction of elevated IOP in patients with open-angle glaucoma or ocular hypertension. Used alone or in conjunction with another IOP-lowering drug (e.g., latanoprost, a carbonic anhydrase inhibitor).

Fixed-combination preparation containing timolol maleate and dorzolamide hydrochloride used to reduce elevated IOP in patients with open-angle glaucoma or ocular hypertension who have not responded adequately (i.e., failed to achieve target IOP as determined after multiple measurements over time) to a topical β-adrenergic blocking agent.

Fixed-combination preparation associated with slightly smaller decrease in IOP than combination therapy with timolol (administered twice daily) and dorzolamide (administered 3 times daily).