Droperidol Injection and Thorazine (Chlorpromazine Tablets)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using chlorproMAZINE together with droperidol can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. In addition, you should let your doctor know if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR CLOSELY: Droperidol has been associated with QT prolongation, torsades de pointes and other serious arrhythmias, and deaths. The concurrent administration of drugs known to increase the QT interval (e.g., phenothiazines) may increase the risk of prolonged QT syndrome. In addition, two case reports have suggested that concomitant administration of chlorpromazine and droperidol may cause agranulocytosis; however, causality was not clearly determined.

MANAGEMENT: The manufacturer recommends extreme caution if droperidol must be given concomitantly with these agents. The dosage of droperidol should be individualized and titrated to the desired effect. Routine vital sign and ECG monitoring is recommended.

Droperidol Injection

Generic Name: droperidol

Brand name: Inapsine

Synonyms: Droperidol

What is Droperidol Injection?

Thorazine (Chlorpromazine Tablets)

Generic Name: chlorpromazine

Brand name: Thorazine, Ormazine, Thorazine Spansule

Synonyms: Thorazine (Injection), Thorazine

What is Thorazine (Chlorpromazine Tablets)?