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Drospirenone and ethinyl estradiol and Hylenex

Determining the interaction of Drospirenone and ethinyl estradiol and Hylenex and the possibility of their joint administration.

Check result:
Drospirenone and ethinyl estradiol <> Hylenex
Relevance: 05.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Larger amounts of hyaluronidase may be required to achieve equivalent dispersing effects if patients are concomitantly receiving large doses of salicylates, cortisone, ACTH, estrogens, or antihistamines. These drugs may render tissues partially resistant to the dispersing action of hyaluronidase.

References
  • "Product Information. Vitrase (hyaluronidase)." Bausch and Lomb, Rochester, NY.
Drospirenone and ethinyl estradiol

Generic Name: drospirenone / ethinyl estradiol

Brand name: Gianvi, Jasmiel, Loryna, Nikki, Ocella, Syeda, Vestura, Yasmin, Yaz, Zarah, Lo-Zumandimine, Zumandimine, Ocella, Yasmin 28, Yaz

Synonyms: Ethinyl Estradiol and Drospirenone

Hylenex

Generic Name: hyaluronidase

Brand name: Amphadase, Hylenex, Vitrase, Wydase, Hydase

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle