Dulaglutide and Sitagliptin and Metformin Tablets

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with sitagliptin has been shown to modestly increase the plasma concentrations of dulaglutide. The mechanism of interaction has not been described. When a single 1.5 mg dose of dulaglutide was administered during multiple dosing of sitagliptin 100 mg to steady state, dulaglutide peak plasma concentration (Cmax) and systemic exposure (AUC) increased by approximately 27% and 38%, respectively. These changes are not considered clinically relevant.

Dulaglutide

Generic Name: dulaglutide

Brand name: Trulicity Pen, Trulicity

Synonyms: n.a.

What is Dulaglutide?

Sitagliptin and Metformin Tablets

Generic Name: metformin / sitagliptin

Brand name: Janumet, Janumet XR

Synonyms: Metformin and sitagliptin, Sitagliptin and Metformin

What is Sitagliptin and Metformin Tablets?