Duobrii Lotion and Flurandrenolide Ointment

• Generic Name: halobetasol / tazarotene topical
• Dosage Forms: lotion
• Other Brand Names: Duobrii

Duobrii Lotion contains a combination of halobetasol and tazarotene. Halobetasol is a highly potent steroid. Tazarotene is a compound similar to vitamin A.

Duobrii Lotion is a prescription medicine used to treat plaque psoriasis (raised, silvery flaking and redness of the skin) in adults.

It is not known if Duobrii is safe and effective in children under 18 years of age.

• Generic Name: flurandrenolide topical
• Dosage Forms: ointment
• Other Brand Names: Cordran, Cordran SP, Cordran Tape, Nolix

Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Generally most effective in acute or chronic dermatoses (e.g., seborrheic or atopic dermatitis, localized neurodermatitis, anogenital pruritus, psoriasis, late phase of allergic contact dermatitis, inflammatory phase of xerosis).

Topical therapy generally preferred over systemic therapy; fewer associated adverse systemic effects.

Topical therapy generally only controls manifestations of dermatoses; eliminate cause if possible.

Topical efficacy may be increased by using a higher concentration or occlusive dressing therapy. (See Administration with Occlusive Dressing under Dosage and Administration.)

Response may vary from one topical corticosteroid preparation to another.

Anti-inflammatory activity may vary considerably depending on the vehicle, drug concentration, site of application, disease, and individual patient.

Flurandrenolide 0.05% ointment is considered to have high-range potency.

Flurandrenolide 0.05% cream is considered to have medium-range potency.