Duragesic and Eliglustat Tartrate

• Generic Name: fentanyl
• Dosage Forms: patch, transdermal system
• Other Brand Names: Duragesic, Abstral, Fentora, Subsys, Actiq, Ionsys, Lazanda, Onsolis, Sublimaze

Duragesic is a skin patch containing fentanyl, an opioid pain medication. An opioid is sometimes called a narcotic.

Duragesic patches are a strong prescription pain medicine. The patches are used to treat moderate to severe chronic pain in opioid-tolerant patients, severe enough to require daily, around-the-clock, long-term opioid treatment.

Duragesic patches are used when other pain treatments such as non-opioid pain medicines or immediate-release opioid medicines do not treat your pain well enough or you cannot tolerate them.

Duragesic patches are not for treating mild or occasional pain or pain from surgery. The patches are not for use to treat pain that is not around-the-clock.

• Generic Name: eliglustat
• Dosage Forms: n.a.
• Other Brand Names: Cerdelga

Long-term treatment of nonneuronopathic (type 1) Gaucher disease in patients who are extensive, intermediate, or poor metabolizers of CYP2D6.

Patient selection and dosing based on CYP2D6 metabolizer status; determine patient's CYP2D6 genotype with an FDA-cleared test prior to initiating therapy.

Ultrarapid CYP2D6 metabolizers may not achieve adequate plasma concentrations to achieve a therapeutic effect. A specific dosage cannot be recommended for patients whose CYP2D6 genotype cannot be determined (indeterminate metabolizers).

Designated an orphan drug by FDA for treatment of type 1 Gaucher disease.