Duragesic-100 skin patch and Erdafitinib
Determining the interaction of Duragesic-100 skin patch and Erdafitinib and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies. MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided. References "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Professional:GENERALLY AVOID: Coadministration with erdafitinib may alter the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme, resulting in increased toxicity or decreased efficacy of these drugs. In vitro, erdafitinib has been shown to be a time-dependent inhibitor as well as inducer of CYP450 3A4. However, no pharmacokinetic data are available from drug interaction studies.
MANAGEMENT: Concomitant use of erdafitinib and sensitive CYP450 3A4 substrates or substrates with narrow therapeutic ranges should generally be avoided.
- "Product Information. Balversa (erdafitinib)." Janssen Products, LP, Horsham, PA.
Generic Name: fentanyl
Brand name: Duragesic, Abstral, Fentora, Subsys, Actiq, Ionsys, Lazanda, Onsolis, Sublimaze
Synonyms: Duragesic Skin Patch, Duragesic
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Duragesic-100 skin patch-Erelzi Prefilled Syringe
- Duragesic-100 skin patch-Erelzi Sensoready Pen
- Duragesic-100 skin patch-Erelzi Subcutaneous
- Duragesic-100 skin patch-Ergocalciferol
- Duragesic-100 skin patch-Ergocalciferol Capsules and Tablets
- Duragesic-100 skin patch-Ergocalciferol Solution
- Erdafitinib-Durahist D
- Erdafitinib-Duramist Plus
- Erdafitinib-Duramorph
- Erdafitinib-Duramorph PF injection
- Erdafitinib-Durapren Injection
- Erdafitinib-DuraProxin ES