Durolane injection and Lidocaine and Benzalkonium
Determining the interaction of Durolane injection and Lidocaine and Benzalkonium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using benzalkonium chloride topical together with sodium hyaluronate. Disinfectants containing benzalkonium chloride topical should not be used for skin preparation before injections. Povidone iodine (Betadine), other skin disinfectants that contain iodine, or alcohol skin preparations are safe for use and are recommended. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Disinfectants containing quaternary ammonium salts should not be used for skin preparation before injections of viscoelastic solutions. Hyaluronic acid will precipitate in the presence of these salts.
MANAGEMENT: Povidone iodine (Betadine), other iodinated skin disinfectants, or alcohol skin preparations are safe for use and are recommended by the manufacturers.
- "Product Information. Orthovisc (hyaluronan)." Ortho Biotech Inc, Bridgewater, NJ.
- "Product Information. Synvisc (viscoelastic solution)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
- "Product Information. Hyalgan (hyaluronidate sodium)." Sanofi Winthrop Pharmaceuticals, New York, NY.
Generic Name: sodium hyaluronate
Brand name: Durolane, Euflexxa, Gel-One, Gelsyn-3, Hyalgan, Supartz, Supartz FX, Visco-3, Trivisc, GenVisc 850, Monovisc, Orthovisc, Synvisc, Synvisc-One
Synonyms: Durolane (injection)
Generic Name: benzalkonium chloride / lidocaine topical
Brand name: A + D Cracked Skin Relief, Bactine, First Aid Antiseptic, GNP Mercuroclear, Medi-First/Lidocaine, SM First Aid Antiseptic, TGT First Aid Cleansing
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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