Dynacirc CR and Simvastatin Oral Suspension
Determining the interaction of Dynacirc CR and Simvastatin Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Isradipine may increase the plasma clearance or decrease the absorption of lovastatin. Plasma lovastatin concentrations may be decreased. Although reduced clinical efficacy of lovastatin has not been demonstrated as a result of this interaction, data are limited. Reduced antihyperlipidemic effects should be anticipated. A similar reaction may occur with other HMG-CoA reductase inhibitors.
- Holtzman J, Finley D, Zhou L, Hassell A "Interaction between isradipine (I) and lovastatin (L) in normal male volunteers." Am Soc Clin Pharmacol Ther 53 (1993): 164
Generic Name: isradipine
Brand name: Dynacirc, Dynacirc CR
Synonyms: Dynacirc CR (Oral), DynaCirc CR
Generic Name: simvastatin
Brand name: Zocor, Flolipid
Synonyms: Simvastatin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dynacirc CR-Simvastatin orally disintegrating tablet
- Dynacirc CR-Simvastatin Tablets
- Dynacirc CR-Sinarest
- Dynacirc CR-Sinarest Nasal
- Dynacirc CR-Sinarest Sinus
- Dynacirc CR-Sine-Off Maximum Strength
- Simvastatin Oral Suspension-Dynapen
- Simvastatin Oral Suspension-Dyphylline
- Simvastatin Oral Suspension-Dyphylline and guaifenesin
- Simvastatin Oral Suspension-Dyphylline and Guaifenesin Liquid
- Simvastatin Oral Suspension-Dyphylline and Guaifenesin Tablets
- Simvastatin Oral Suspension-Dyphylline Oral, Intramuscular