Dynacirc CR and Somatuline Depot
Determining the interaction of Dynacirc CR and Somatuline Depot and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Lanreotide can sometimes slow your heart rate, and using it with isradipine may further increase that effect. This can lead to an excessively slow heartbeat, heart block, low pulse, headache, dizziness, or fainting. Let your doctor know if you experience any of these symptoms or your condition changes during treatment with these medications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Somatostatin analogs (e.g., octreotide, lanreotide) can decrease heart rate and may potentiate the bradycardic effects of drugs like beta-blockers, calcium channel blockers, digitalis glycosides, and certain antiarrhythmic agents (e.g., class I antiarrhythmics, adenosine, amiodarone). Octreotide has commonly been associated with bradycardia (less than 50 bpm), conduction abnormalities, and arrhythmias in acromegalic patients. Occasional cases of sinus bradycardia and ventricular tachycardia have also been reported with lanreotide.
MANAGEMENT: Caution is advised if somatostatin analogs are prescribed with agents that exhibit bradycardic effects, including ophthalmic formulations of beta-blockers. Heart rate and blood pressure should be monitored.
- "Product Information. Sandostatin (octreotide)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
- "Product Information. Somatuline Depot (lanreotide)." Ipsen Inc, Milford, MA.
Generic Name: isradipine
Brand name: Dynacirc, Dynacirc CR
Synonyms: Dynacirc CR (Oral), DynaCirc CR
Generic Name: lanreotide
Brand name: Somatuline Depot
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Dynacirc CR-Somavert
- Dynacirc CR-Sominex
- Dynacirc CR-Somnote
- Dynacirc CR-Sonahist
- Dynacirc CR-Sonahist DM
- Dynacirc CR-Sonata
- Somatuline Depot-Dynapen
- Somatuline Depot-Dyphylline
- Somatuline Depot-Dyphylline and guaifenesin
- Somatuline Depot-Dyphylline and Guaifenesin Liquid
- Somatuline Depot-Dyphylline and Guaifenesin Tablets
- Somatuline Depot-Dyphylline Oral, Intramuscular