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Dysport and IncobotulinumtoxinA

Determining the interaction of Dysport and IncobotulinumtoxinA and the possibility of their joint administration.

Check result:
Dysport <> IncobotulinumtoxinA
Relevance: 07.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using abobotulinumtoxinA together with incobotulinumtoxinA. These medications are similar, and using them together or within several months of each other may increase the risk of certain side effects such as excessive muscle weakness, blurred or double vision, and difficulty breathing, swallowing, or speaking. In rare cases, swallowing and breathing difficulties may be life-threatening, so you should seek immediate medical attention if they occur. These medications should only be given by your healthcare provider and under direct medical supervision. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The effect of administering different botulinum neurotoxin serotypes concurrently or within several months of one another is unknown. Excessive weakness may be exacerbated by another administration of botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin.

MANAGEMENT: Due to their similar pharmacologic profiles, the potential for additive neuromuscular blocking effects and paralysis should be considered.

References
  • "Product Information. Botox (onabotulinumtoxin A)." Allergan Inc, Irvine, CA.
  • "Product Information. Dysport (abobotulinumtoxinA)." Tercica Inc, Brisbane, CA.
  • "Product Information. Myobloc (botulinum toxin type B)" Elan Pharmaceuticals, S. San Francisco, CA.
  • "Product Information. Xeomin (botulinum toxin type A (obsolete) (botulinum toxin type A))." Merz Pharmaceuticals, Greensboro, NC.
Dysport

Generic Name: abobotulinumtoxinA

Brand name: Dysport

Synonyms: n.a.

IncobotulinumtoxinA

Generic Name: incobotulinumtoxinA

Brand name: Xeomin

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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