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EContra EZ and Ulipristal Acetate

Determining the interaction of EContra EZ and Ulipristal Acetate and the possibility of their joint administration.

Check result:
EContra EZ <> Ulipristal Acetate
Relevance: 12.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ulipristal may temporarily reduce the effectiveness of hormonal contraceptives. Therefore, you should use an additional method of birth control such as condoms following treatment with ulipristal until your next menstrual period. You should discuss your contraceptive options with your healthcare provider. Do not combine ulipristal with other emergency contraception such as Plan B. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADDITIONAL CONTRACEPTION RECOMMENDED: Coadministration with ulipristal may reduce the efficacy of combination hormonal contraceptives. There are no clinical data regarding use of ulipristal with regular hormonal contraceptives. However, due to its high-affinity binding to the progesterone receptor, ulipristal may interfere with the pharmacologic action of progestogens.

GENERALLY AVOID: The concomitant use of ulipristal and emergency contraception containing levonorgestrel is not recommended.

MANAGEMENT: After emergency contraception with ulipristal, routine contraception should be continued or initiated as soon as possible to ensure ongoing prevention of pregnancy. Patients who receive contraceptives containing levonorgestrel or other progestogens should also use a reliable barrier method of contraception until their next menstrual period.

References
  • "Product Information. ella (ulipristal)." Afaxys Inc., Charleston, SC.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
EContra EZ

Generic Name: levonorgestrel

Brand name: EContra EZ, Fallback Solo, My Way, Next Choice, Opcicon One-Step, Plan B One-Step, React, Aftera, EContra One-Step, My Choice, My Way, New Day, Next Choice One Dose, Take Action, Kyleena, Liletta, Mirena, Skyla

Synonyms: n.a.

Ulipristal Acetate

Generic Name: ulipristal

Brand name: Ella, Ella

Synonyms: Ulipristal

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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