Eculizumab Intravenous and Gianvi

• Generic Name: eculizumab
• Dosage Forms: n.a.
• Other Brand Names: Soliris

Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). Eculizumab helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.

Eculizumab is also used to treat a serious kidney disorder called atypical hemolytic uremic syndrome (aHUS).

Eculizumab injection is also used to treat a nerve and muscle disease called generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AchR) antibody positive.

Eculizumab injection is a monoclonal antibody that works on the immune system.

Eculizumab is available only under a restricted distribution program called Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: drospirenone / ethinyl estradiol
• Dosage Forms: tablets
• Other Brand Names: Gianvi, Jasmiel, Loryna, Nikki, Ocella, Syeda, Vestura, Yasmin, Yaz, Zarah, Lo-Zumandimine, Zumandimine, Ocella, Yasmin 28, Yaz

Gianvi is a combination birth control pill containing female hormones that prevent ovulation (the release of an egg from an ovary). Gianvi also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Gianvi is used as contraception to prevent pregnancy. This medicine is also used to treat moderate acne in women who are at least 14 years old and have started having menstrual periods, and who wish to use birth control pills.

Yaz is also used to treat the symptoms of premenstrual dysphoric disorder (PMDD), such as anxiety, depression, irritability, trouble concentrating, lack of energy, sleep or appetite changes, breast tenderness, joint or muscle pain, headache, and weight gain.

Gianvi may also be used for purposes not listed in this medication guide.