Eculizumab Intravenous and Optiray

• Generic Name: eculizumab
• Dosage Forms: n.a.
• Other Brand Names: Soliris

Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). Eculizumab helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.

Eculizumab is also used to treat a serious kidney disorder called atypical hemolytic uremic syndrome (aHUS).

Eculizumab injection is also used to treat a nerve and muscle disease called generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AchR) antibody positive.

Eculizumab injection is a monoclonal antibody that works on the immune system.

Eculizumab is available only under a restricted distribution program called Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: ioversol
• Dosage Forms: injection
• Other Brand Names: Optiray 240, Optiray 300, Optiray 320, Optiray 350, Optiray 160

Ioversol is a radiopaque (RAY dee oh payk) contrast agent. Ioversol contains iodine, a substance that absorbs x-rays. Contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Ioversol is used to help diagnose certain disorders of the heart, brain, and blood vessels.

Ioversol may also be used for purposes not listed in this medication guide.