Eculizumab Intravenous and Soliqua

• Generic Name: eculizumab
• Dosage Forms: n.a.
• Other Brand Names: Soliris

Eculizumab injection is used to treat a type of blood disease called paroxysmal nocturnal hemoglobinuria (PNH). Eculizumab helps reduce red blood cell destruction or breakdown (hemolysis) in patients with PNH.

Eculizumab is also used to treat a serious kidney disorder called atypical hemolytic uremic syndrome (aHUS).

Eculizumab injection is also used to treat a nerve and muscle disease called generalized myasthenia gravis (gMG) in patients who are anti-acetylcholine receptor (AchR) antibody positive.

Eculizumab injection is a monoclonal antibody that works on the immune system.

Eculizumab is available only under a restricted distribution program called Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: insulin glargine / lixisenatide
• Dosage Forms: injection, solution
• Other Brand Names: Soliqua 100/33

Soliqua 100/33 contains a combination of insulin glargine and lixisenatide. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. Lixisenatide is a diabetes medicine that helps your pancreas produce insulin more efficiently.

Soliqua 100/33 is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Soliqua 100/33 is not for treating type 1 diabetes.