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Edecrin Sodium and Mesantoin

Determining the interaction of Edecrin Sodium and Mesantoin and the possibility of their joint administration.

Check result:

Edecrin Sodium <> Mesantoin

Relevance: 12.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Some hydantoins may reduce the gastrointestinal absorption of some loop diuretics. Serum diuretic concentrations and diuretic effects after oral dosing may be decreased. Data are available for furosemide and phenytoin only. Increases in diuretic dosage may be necessary.

References

Ahmad S "Renal insensitivity to frusemide caused by chronic anticonvulsant therapy." Br Med J 3 (1974): 657-9
Fine A, Henderson IS, Morgan DR "Malabsorption of frusemide caused by phenytoin." Br Med J 2 (1977): 1601-2

Edecrin Sodium

Generic Name: ethacrynic acid

Brand name: Sodium Edecrin, Edecrin, Edecrin Sodium

Synonyms: Sodium Edecrin

What is Edecrin Sodium?

Mesantoin

Generic Name: mephenytoin

Brand name:

Synonyms: n.a.

What is Mesantoin?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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