E.E.S. Granules Oral and Rosuvastatin
Determining the interaction of E.E.S. Granules Oral and Rosuvastatin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with erythromycin may slightly decrease the plasma concentrations of rosuvastatin. The mechanism may involve an increase in gut motility caused by erythromycin. According to the product labeling for rosuvastatin, erythromycin (500 mg four times a day for 7 days) decreased the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of rosuvastatin (80 mg single dose) by 31% and 20%, respectively. These reductions are not considered clinically significant.
- "Product Information. Crestor (rosuvastatin)." AstraZeneca Pharma Inc, Mississauga, ON.
Generic Name: erythromycin
Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV
Synonyms: E.E.S. Granules (Oral), EES
Generic Name: rosuvastatin
Brand name: Crestor, Ezallor Sprinkle
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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